Complior Analyse
PWV and Central Blood Pressure Analysis
Advanced system for the non-invasive assessment of arterial stiffness, Pulse Wave Velocity (PWV), and central hemodynamics
The Complior Analyse is a system designed to measure Pulse Wave Velocity (PWV) and assess arterial stiffness non-invasively.1,2 The assessment of large artery stiffness provides relevant information for cardiovascular health research.4
The system uses piezoelectric sensors to record pulse waves at different arterial sites. The acquired signals allow PWV calculation and analysis of the carotid pressure waveform to estimate central hemodynamic parameters.2,3
Main Features
Technology for Arterial Function Analysis and Hemodynamic Assessment
The Complior Analyse combines piezoelectric sensors and analysis software to record pulse waves and assess arterial stiffness.
The system can be used in clinical studies and cardiovascular research, supporting the analysis of arterial function and hemodynamic parameters.
Simultaneous Pulse Wave Acquisition
Records arterial signals at different anatomical sites to calculate transit time and pulse wave velocity.
High-Precision Piezoelectric Sensors
Uses up to four independent, color-coded sensors to facilitate arterial positioning.
Carotid Waveform Assessment
Records the carotid pressure waveform to estimate parameters related to central blood pressure.3
Aortic Stiffness Analysis
Assesses carotid-femoral pulse wave velocity, which is used in the non-invasive evaluation of aortic stiffness.1,4
Pressure Waveform Morphology Analysis
Analyzes parameters such as systolic pressure, pulse pressure, augmentation pressure, and augmentation index.
Automated
Acquisition
Monitors signal quality and assists in selecting recordings for analysis.
Intuitive Piezoelectric Sensors
Equipped with up to four dedicated piezoelectric pressure sensors, the Complior Analyse facilitates connection to the acquisition unit through an intuitive color-coding system that ensures quick setup and helps prevent errors.1
Carotid Sensor
Records the carotid pulse waveform and is used in the assessment of central blood pressure and PWV.
Femoral Sensor
Used together with the carotid sensor to measure carotid-femoral PWV.
Radial Sensor
Enables pulse wave recordings along the carotid-radial arterial segment.
Distal Sensor
Designed for studies involving peripheral arteries, such as the tibial and dorsalis pedis arteries.
Pulse Wave Velocity (PWV)
Assessment of Aortic Stiffness and Vascular Function
Pulse Wave Velocity (PWV) is the speed at which a pressure wave travels along an arterial segment. Carotid-femoral PWV is widely used in the non-invasive assessment of aortic stiffness.1,4
Measurement Principle
PWV is calculated as the ratio between the distance traveled by the pulse wave and the time required for its propagation.1
Formula: PWV =
Gold
Standard
Carotid-femoral PWV is recommended for the assessment of aortic stiffness.4
Cardiovascular Risk Indicator
PWV supports the investigation of arterial stiffness and cardiovascular risk.4
Reference
Curves
Allows comparison of results with reference values, when available in the software.
Multiple
Segments
Allows acquisition to be configured with different sensors to assess arterial segments.
Central Blood Pressure
Central Hemodynamic Assessment
Central Hemodynamic Parameters
The software displays parameters derived from pressure waveform analysis, related to cardiac and arterial function:3
| SBP: Systolic Blood Pressure | DBP: Diastolic Blood Pressure |
| PP: Pulse Pressure | MAP: Mean Arterial Pressure |
| AIx: Augmentation Index | AP: Augmentation Pressure |
| P1: First Systolic Shoulder Pressure | PES: End-Systolic Pressure |
| Max dP/dt: Maximum Rate of Pressure Rise | LVET: Left Ventricular Ejection Time |
| DT: Diastolic Time | As / Ad: Systolic and Diastolic Areas |
Carotid Pressure Waveform Analysis
The Complior Analyse records the pressure waveform in the carotid artery for the analysis of central hemodynamic parameters.3
Carotid Waveform Recording: The piezoelectric sensor records the pressure waveform directly over the carotid artery.
Signal Calibration: The carotid waveform is calibrated using peripheral blood pressure values to estimate central parameters.3
Complior Analyse Software
Intuitive Interface and Advanced Clinical Data Management
The Complior Analyse software was developed to optimize clinical workflows and research, providing precise, automated, real-time analysis of hemodynamic parameters and arterial stiffness.
- Automated Real-Time Analysis: Instant processing of time delay and automatic calculation of pulse wave velocity (PWV) and central blood pressure.
- Signal Quality Control: Intelligent algorithms assist the operator in acquiring high-fidelity signals, supporting measurement reproducibility.
- Customizable Reports: Fast generation of clear, structured reports for clinical documentation, including waveform graphs and comparisons with reference values.
- Integrated Database: Secure storage of patient records for longitudinal follow-up and simplified data export for scientific studies.
Simple, Reproducible, and Automated Examination Protocol
- With the patient lying supine and at rest, the operator launches the Complior Analyse software and enters the patient information.
- The operator locates the arteries and marks the carotid and femoral measurement sites.
- The operator measures the distance between the carotid and femoral arterial sites and enters the value (in mm) into the Complior Analyse software.
- Blood pressure is measured using a sphygmomanometer, and the values are entered into the software.
- The operator positions the carotid sensor using the appropriate support.
- The operator positions the femoral sensor at the marked site and starts acquisition, monitoring the quality indicators displayed by the software.
- The software displays the PWV results and the available hemodynamic parameters.
Scientific Background and Validation
Scientific Evidence in Vascular Assessment
Pulse wave velocity (PWV) measurement methodology has been evaluated in validation studies and clinical applications.1
The reproducibility of aortic PWV measured using the Complior Analyse has also been investigated in specific studies.2
Methodological studies have also evaluated the reproducibility of pressure waveform analysis using this device.3
In addition, international scientific recommendations highlight the importance of standardizing methods used to assess arterial stiffness.4
The Complior Analyse provides tools for arterial signal acquisition and analysis, supporting research into vascular stiffness and hemodynamics.
Technical Specifications
Compact system integrating piezoelectric sensors and software for arterial stiffness and central hemodynamic analysis.
Feature |
Specification |
| Acquisition Channels | Up to 4 channels |
| Acquisition Time | Up to 30 seconds |
| Dimensions (H × W × D) | 43 × 150 × 128 mm |
| Weight | 450 g (excluding computer) |
| Power Supply | USB 5 V |
| Minimum Processor | 1 GHz |
| Minimum RAM | 256 MB |
| Connections | 2 USB ports |
| Operating System | Windows |
| Operating Temperature | +10 to +40 °C |
| Relative Humidity | Below 95% |
| Stated Classification | Class IIa – CE |
| Stated Standards | IEC 601-1-1 and IEC 601-1-2 |
References
- Asmar R, Benetos A, Topouchian J, Laurent P, Pannier B, Brisac AM, Target R, Levy BI. Assessment of arterial distensibility by automatic pulse wave velocity measurement. Validation and clinical application studies. Hypertension. 1995;26(3):485–490. DOI: 10.1161/01.HYP.26.3.485.
- Pereira T, Maldonado J. Reproducibility of aortic pulse wave velocity as assessed with the new Complior Analyse. Blood Pressure Monitoring. 2014. DOI: 10.1097/MBP.0000000000000038.
- Pulse wave analysis reproducibility with the Complior Analyse device: a methodological study. 2018. PubMed PMID: 29537992. Complete bibliographic details to be confirmed.
- Townsend RR, et al. Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness: A Scientific Statement from the American Heart Association. Hypertension. 2015;66(3):698–722.
Need More Information?
Access our documentation and technical resources for more information about the product.
Biolink® is the representative of Complior Analyse in Brazil and South America. We provide sales support, technical support, and specialized assistance for the equipment and its applications in research and arterial stiffness assessment.
Contact us to request a quotation.